Spoiled Discussion of Permutation City, A Fire Upon The Deep, and Eliezer's Mega Crossover
Permutation City is an awesome novel that was written in 1994. Even if the author, Greg Egan, used a caricature of this community as a bad guy in a more recent novel, his work is still a major influence on a lot of people around these parts who have read it. It dissolves so many questions around uploading and simulation that it's hard for someone who has read the book to talk about simulationist metaphysics without wanting to reference the novel... but doing that runs into constraints imposed by spoiler etiquette.
So go read Permutation City if you haven't read it already because it's philosophically important and a reasonably fun read.
In the meantime, if you haven't then you should also read A Fire Upon The Deep by Vernor Vinge (of "singularity" coining fame) and then read Eliezer's fan fic The Finale of the Ultimate Meta Mega Crossover which references both of them in interesting ways to make substantive philosophical points and doesn't take too long to read.
In the comments below there will be discussion that has spoilers for all three works.
The idea that a consciousness can exist within an alternate reading frame on a system that is not conscious in my own frame, as Peer exists within the City, does significant violence to my intuitions about consciousness.
The idea that the alternate frame can be temporally discontiguous with my own... that is, that events A and B can occur in both frames but in a different order... does additional violence to my intuitions about time.
That said, I have no reason to expect my intuitions about consciousness or time to reflect the way the universe actually is. (Of course, that doesn't mean any particular contradictory theory is right.)
That said, without the possibility of intentional causal interaction with such alternate-frame consciousnesses, I'm indifferent to them: I can't see any reason why I should care whether it's true. I feel more or less the same way as I do about the possibility of epiphenomenal spirits, or epiphenomenal Everett branches: if they are in principle unable to interact causally with me, if no observation I can ever make will go differently based on their existence or nonexistence, then I simply don't care whether they exist or not.
I don't endorse that apathy, though. It mostly comes out of a motivational psychology in which believing that future events are significantly influenced by my actions is important to motivating those actions, and I don't especially endorse that sort of psychology, despite instantiating one.
I don't see the connection to Searle's CR.
How about, instead of an opaquely described "alternate reading frame", we consider homomorphic encryption. Take some uploads in a closed environment, homomorphically encrypt the whole thing, throw away the decryption key, and then start it running. I think this matches Peer's situation in all relevant aspects: The information about the uploads exists in the ordinary computational basis (not talking Dust Theory here), and there is a short and fast program to extract it, but it's computationally intractable to find that program if you don't know the secret. The difference is that this way it's much more obvious what that secret would look like.