Open thread, September 15-21, 2014

If it's worth saying, but not worth its own post (even in Discussion), then it goes here.


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I'm posting here on behalf of Brent Dill, known here and elsewhere as ialdabaoth-- you may have enjoyed some of his posts. If you read the comments at SSC, you'll recognize him as a contributor of rare honesty and insight. If you'd had the chance to talk with him as much as I have, you'd know he's an awesome guy: clever, resourceful, incisive and deeply moral. Many of you see him as admirable, most as relatable, some as a friend, and more, I hope, as a member of our community.

He could use some help.

Until last Thursday he was gainfully employed as a web developer for a community college in Idaho. Recently, he voluntarily mentioned to his boss that he was concerned that seasonal affective disorder was harming his job performance, who mentioned it to his boss, who suggested in all good faith that Brent should talk to HR to see if they might help through their Employee Assistance Program. In Brent's words: "Instead, HR asked me a lot of pointed questions about when my performance could turn around and whether I wanted to work there, demanded that I come up with all the solutions (after I admitted that I was already out of brainpower and feeling intimidated), and then directed me to turn in my keys and go home, and that HR would call me on Monday to tell me the status of my employment." Now, at the end of the day Tuesday, they still haven't let him know what's happening, but it doesn't look good.

I think we can agree that this is some of the worst horseshit.

On the other hand, he's been wanting to get out of Idaho and into a city with an active rationalist community for a while, so in a sense this is an opportunity. Ways to help: Brent needs, in order of priority: a job, a place to stay, and funds to cover living and moving expenses-- details below. Signal boosts and messages of support are also helpful and appreciated. Ways NOT to help: Patronizing advice/other-optimizing (useful information is of course welcome), variations on 'cool story bro' (the facts here have been corroborated to my satisfaction with hard-to-fake evidence), disrespect in general.

1. Job: Leads and connections would help more than anything else. He's looking to end up, again, in a good-sized city with an active rationalist community. Candidates include the Bay Area, New York, Boston, Columbus, San Diego, maybe DC or Ann Arbor. He has an excessively complete resume here, but, in short: C#/.NET and SQL developer, also computer game development experience, tabletop board/card game design experience, graphic art and user interface experience, and some team leadership / management experience.

2. Crash space: If you are in one of the above cities, do you have/know of a place for a guy and his cat? How much will it cost, and when will it be available? Probably he'll ultimately want a roommate situation, but if you're willing to put him up for a short time that's also useful information.

3. Funds: Brent is not now in immediate danger of going hungry or homeless, but a couple of months will exhaust his savings, and (although it is hard to know in the current state of things) he has been told that the circumstances constitute "cause" sufficient to keep him from drawing unemployment. Moving will almost certainly cost more than he has on hand. There is a possible future in which he runs out of money stranded in Idaho, which would be not good.

If you feel moved to help, he has set up a gofundme account here. (The goal amount is set at his calculated maximum expenses, but any amount at all would help and be greatly appreciated-- he would have preferred not to set a funding goal at all.) Though Brent has pledged to eventually donate double the amount he raises to Effective Altruist causes, we wouldn't like you to confuse contributing here with charitable giving. Rather, you might want to give in order to show your appreciation for his writing, or to express your solidarity in the struggles and stigma around mental illness, or as a gesture of friendship and community, or just to purchase fuzzies. Also, you can make him do stuff on Youtube, you know, if you want.

Thank you so much for your time and kindness. -Elissa Fleming

Official update: HR "explored every possible option" but "ultimately we have to move forward with your termination process" after "making certain there was unanimous consensus".

Apparently several people in my now ex-office are upset about this.

Is Austin on the list? I work at a not-evil tech startup called SchoolAdmin that does school admissions software for a mix of public/private/charter schools. We're not hiring devs right now, but that might possibly change since we have a product manager coming in October. The company is REALLY not evil; we've had three different people come down with mental or physical health issues, and the president's mantra has been 'your job is to get better' in every case.

I could possibly also offer a place to crash, I've got a futon, a study it could be moved to, and already have cats.

That narrative is unambiguously a case of illegal discrimination. Idaho law Defines:

"Disability" means a physical or mental condition of a person, whether congenital or acquired, which constitutes a substantial limitation to that person and is demonstrable by medically accepted clinical or laboratory diagnostic techniques. A person with a disability is one who (a) has such a disability, or (b) has a record of such a disability, or (c) is regarded as having such a disability;

and

It shall be a prohibited act to discriminate against a person because of, or on the basis of, disability in [employment]... provided that the prohibition against discrimination because of disability shall not apply if the particular disability, even with a reasonable accommodation, prevents the performance of the work required in that job.

I am also very confused as to how actual HR drones in an actual HR department wouldn't be familiar with the law and able to create a suitable enough pretext for termination.

I already mentioned the A.D.A. to Ialdabaoth, but fighting a discrimination case probably takes more money than he's looking to raise to move, as well as being psychologically exhausting.

I don't have any sensible way of learning about current affairs. I don't consume broadcast or print news. Most news stories reach me through social media, blogs, word of mouth or personal research, and I will independently follow up on the ones I think are worthy of interest. This is nowhere near optimal. It means I will probably find out about innovations in robotic bees before I find out about natural disasters or significant events in world politics.

Regular news outlets seem to be messy, noisy attention traps, rather than the austere factual repositories I wish them to be. Quite importantly, there seems to be a lot of stuff in the news that isn't actually news. I'm pretty sure smart people with different values will converge on what a lot of this stuff is.

Has this problem been solved already? I'm willing to put in time/effort/money for minimalist, noise-free, sensibly-prioritised news digest that I care about.

ETA: Although I haven't replied to all these responses individually, they seem very useful and I will be following them up. Thanks!

What sort of current events do you want to find out about how quickly, and why?

You should consider, if you haven't already, the possibility that the value of learning about such things quickly is almost always almost exactly zero. Suppose e.g. there's an enormous earthquake half-way around the world from you, and many thousands of people die. That's a big deal, it's very important -- but what immediate difference should it make to your life?

One possibility: you might send a lot of money to a charity working in the affected place. But it seems unlikely to me that there's much real difference in practice between doing so on the day of the disaster and doing it a week later.

Another possibility (albeit a kinda callous one): it may come up in conversation and you may not want to sound bad. But I bet that in practice "social media, blogs, word of mouth or personal research" do just fine at keeping you sufficiently up to date that you don't sound stupid or ignorant. In any case, what you need to know about in order to sound up to date is probably roughly what you get from existing news sources, rather than from a hypothetical new source of genuinely important, sensibly prioritized news.

I can't find it, but I once read an article from a guy a trust about how he just stopped following news, assuming that if anything sufficiently important happened, he'd find out about it anyway. His quality of life immediately rose. Having followed this approach for a few years now, I would suggest consuming zero news (is minimalist, completely devoid of noise, and exceptionally well-organized).

"Remember, if it’s in the news don’t worry about it. The very definition of news is “something that almost never happens.” When something is so common that it’s no longer news — car crashes, domestic violence — that’s when you should worry about it." - Bruce Schneier

Wikipedia's current events portal is relatively minimalist and low-noise. It's not prioritized very impressively.

According to the efficient market hypothesis index funds should be the best way for the average person to gain a return from investment. Now there is a plethora of indices to invest in. How should one find the 'best' one?

Further, only a relatively small part of return generating assets are captured in publically tradeable assets. What about private equity and real estate, huge parts of the economy?

Funds take a fraction of the earnings out, as management fees, and you want the fund that charges the lowest such fees. The early retirement blogs I read seem to agree on Vanguard being the best choice, at least in the US.

An interesting paper. The abstract says:

Rationality leads people to imitate those with similar tastes but different information. But people who imitate common sources develop correlated beliefs, and rationality demands that later social learners take this correlation into account. This implies severe limits to rational imitation. We show that (i) in most natural observation structures besides the canonical single-file case, full rationality dictates that people must “anti-imitate” some of those they observe; and (ii) in every observation structure full rationality dictates that people imitate, on net, at most one person and are imitated by, on net, at most one person, over any set of interconnected players. We also show that in a very broad class of settings, any learning rule in which people regularly do imitate more than one person without anti-imitating others will lead to a positive probability of people converging to confident and wrong long-run beliefs.

I have a notion that an FAI will be able to create better friends and lovers for you than actual humans could be. Family would be a more complex case if you value the history as well as the current experience.

I'm not talking about catgirls-- if some difficulties in relationships are part of making relationships better in the long haul, then the FAI will supply difficulties.

If people eventually have relationships with FAI-created humans rather than humans generated by other means, is this a problem?

It Ain't Necessarily So: Why Much of the Medical Literature Is Wrong

Some of the material will be familiar, but there are examples I hadn't seen before of how really hard it is to be sure you've asked the right question and squeezed out the sources of error in the answer.

What follows is what I consider to be a good parts summary-- if you want more theory, you should read the article.

Consider a study published in the NEJM that showed an association between diabetes and pancreatic cancer.[3] The casual reader might conclude that diabetes causes pancreatic cancer. However, further analysis showed that much of the diabetes was of recent onset. The pancreatic cancer preceded the diabetes, and the cancer subsequently destroyed the insulin-producing islet cells of the pancreas. Therefore, this was not a case of diabetes causing pancreatic cancer but of pancreatic cancer causing the diabetes.

....

To illustrate the point, consider the ISIS-2 trial,[8] which showed reduced mortality in patients given aspirin after myocardial infarction. However, subgroup analyses identified some patients who did not benefit: those born under the astrological signs of Gemini and Libra; patients born under other zodiac signs derived a clear benefit with a P value < .00001.

I guessed at a seasonal effect, but Gemini and Libra aren't adjacent signs.

The frequency of these false-positive studies in the published literature can be estimated to some degree.[2] Consider a situation in which 10% of all hypotheses are actually true. Now consider that most studies have a type 1 error rate (the probability of claiming an association when none exists [ie, a false positive]) of 5% and a type 2 error rate (the probability of claiming there is no association when one actually exists [ie, a false negative)] of 20%, which are the standard error rates presumed by most clinical trials. This allows us to create the following 2x2 table.

I didn't realize that the false negative effect (not seeing a relationship when there actually is one) is higher than the false positive rate. This might mean that a lot of useful medical tools get eliminated before they'can be explored.

Also (credit given to Seth Roberts), if a minority of people respond very well to a treatment being tested, this is very unlikely to be explored because the experiment is structured to see whether the treatment is good for people in general (actually, people in general in the group being tested). This wasn't in the NEJM piece.

One classic example of selection bias occurred in 1981 with a NEJM study showing an association between coffee consumption and pancreatic cancer.[15] The selection bias occurred when the controls were recruited for the study. The control group had a high incidence of peptic ulcer disease, and so as not to worsen their symptoms, they drank little coffee. Thus, the association between coffee and cancer was artificially created because the control group was fundamentally different from the general population in terms of their coffee consumption. When the study was repeated with proper controls, no effect was seen.[16]

....

Information bias, as opposed to selection bias, occurs when there is a systematic error in how the data are collected or measured. Misclassification bias occurs when the measurement of an exposure or outcome is imperfect; for example, smokers who identify themselves as nonsmokers to investigators or individuals who systematically underreport their weight or overreport their height.[17] A special situation, known as recall bias, occurs when subjects with a disease are more likely to remember the exposure under investigation than controls. In the INTERPHONE study, which was designed to investigate the association between cell phones and brain tumors, a spot-check of mobile phone records for cases and controls showed that random recall errors were large for both groups with an overestimation among cases for more distant time periods.[18] Such differential recall could induce an association between cell phones and brain tumors even if none actually exists.

::::

An interesting type of information bias is the ecological fallacy. The ecological fallacy is the mistaken belief that population-level exposures can be used to draw conclusions about individual patient risks.[4] A recent example of the ecological fallacy, was a tongue-in-cheek NEJM study by Messerli[19} showing that countries with high chocolate consumption won more Nobel prizes. The problem with country-level data is that countries don't eat chocolate, and countries don't win Nobel prizes. People eat chocolate, and people win Nobel prizes. This study, while amusing to read, did not establish the fundamental point that the individuals who won the Nobel prizes were the ones actually eating the chocolate.[20]

On the other hand, if you want to improve the odds of your children winning a Nobel, maybe you should move to a chocolate-eating country.

.....

A 1996 study sought to compare laparoscopic vs open appendectomy for appendicitis.[29] The study worked well during the day, but at night the presence of the attending surgeon was required for the laparoscopic cases but not the open cases. Consequently, the on-call residents, who didn't like calling in their attendings, adopted a practice of holding the translucent study envelopes up to the light to see if the person was randomly assigned to open or laparoscopic surgery. When they found an envelope that allocated a patient to the open procedure (which would not require calling in the attending and would therefore save time), they opened that envelope and left the remaining laparoscopic envelopes for the following morning. Because cases operated on at night were presumably sicker than those that could wait until morning, the actions of the on-call team biased the results. Sicker cases preferentially got open surgery, making the outcomes of the open procedure look worse than they actually were.[30] So, though randomized trials are often thought of as the solution to confounding, if randomization is not handled properly, confounding can still occur. In this case, an opaque envelope would have solved the problem.

Remembering that humans aren't especially compliant is hard.

From reading Guinea Pig Zero: The Journal for Human Research Subjects-- human beings are not necessarily going to comply with onerous food regimes. I expect that most who don't simply don't want to, but the magazine had the argument of not wanting to comply because the someone who's a human research subject is never going to be able to afford treatment based on the results of the research.

If you liked Scott Alexander's essay, Meditations on Moloch, you might like this typographic poster-meme I made. It was a minor success on Facebook.

(If you haven't read Scott Alexander's essay, Meditations on Moloch, then you might want to check it out. As Stuart Armstrong said, it's a beautiful, disturbing, poetical look at the future.)

In the interest of trying out stuff outside the usual sphere-of-things-that-I'm-doing, I now have a fashion/lifestyle blog.

It's in Finnish, but it has a bunch of pictures of me, which ought to be language-neutral. Also my stuffed animals. (And yes, I know that I need a better camera.)

Hi. I'm Portuguese and live near Lisbon. Are there any LWers out there that live nearby?

The latest survey (2013) shows zero people living in Portugal, and so I feel a bit lonely out here, especially when I read the locations for the LW meetups. They seem so close, only not really...

I guess I could make an effort to start my own meetup in Lisbon or something, maybe, I don't know. I am a little shy and I don't think I am capable of starting something like that on my own.

I work in academia, in the field of computer science, and thus am surrounded by people that would find this website appealing. I have in fact introduced this site (sometimes subtly) to some people I know, but haven't seen anyone taking the time to read the Sequences and get in sync with this community. I want to try harder, though.

What would you say is the most effective way of capturing the interest on this site? My tools are Facebook, and the chance to make a presentation about anything I want at the University and getting an audience of at most 30 people.