Alice: "I just flipped a coin [large number] times. Here's the sequence I got:
(Alice presents her sequence.)
Bob: No, you didn't. The probability of having gotten that particular sequence is 1/2^[large number]. Which is basically impossible. I don't believe you.
Alice: But I had to get some sequence or other. You'd make the same claim regardless of what sequence I showed you.
Bob: True. But am I really supposed to believe you that a 1/2^[large number] event happened, just because you tell me it did, or because you showed me a video of it happening, or even if I watched it happen with my own eyes? My observations are always fallible, and if you make an event improbable enough, why shouldn't I be skeptical even if I think I observed it?
Alice: Someone usually wins the lottery. Should the person who finds out that their ticket had the winning numbers believe the opposite, because winning is so improbable?
Bob: What's the difference between finding out you've won the lottery and finding out that your neighbor is a 500 year old vampire, or that your house is haunted by real ghosts? All of these events are extremely improbable given what we know of the world.
Alice: There's improbable, and then there's impossible. 500 year old vampires and ghosts don't exist.
Bob: As far as you know. And I bet more people claim to have seen ghosts than have won more than 100 million dollars in the lottery.
Alice: I still think there's something wrong with your reasoning here.
Substantial? No - it adds up to normality. Interesting? Yes.
Imagine two situations of equal improbability:
In one, Alice flips a coin N times in front of a crowd, and achieves some specific sequence M.
In the other, Alice flips a coin N / 2 times in front of a crowd, and achieves some specific sequence Q; she then opens an envelope, and reveals a prediction of exactly the sequence that she just flipped.
These two end results are equally improbable (both end results encode N bits of information - to see this, imagine that the envelope contained a different sequence than she flipped), but we attach significance to one result (appropriately) and not the other. What's the difference between the two situations?
I do not think these events are equally improbable (thus, equally probable).
The specific sequence, M, is some sequence in the space of all possible sequences; "... achieves some specific sequence M" is like saying "there exists an M in the space of all sequences such that N = M." That will always be true—that is, one can always retroactively say "Alice's end-result is some specific sequence."
On the other hand, it's a totally different thing to say "Alice's end-result is some specific sequence which she herself picked out before flipping the coin."